الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Acute kidney injury (AKI) results in a significant burden for the society in terms of health resource use during the acute phase, and the potential long-term sequelae including development of chronic kidney disease (CKD) and kidney failure. The aim of this study is to investigate the association between systemic hemodynamic indices and the risk of development or progression of AKI in critically ill children. Methods: This is a cohort study based on data collected for 60 critically ill children with or without cardiovascular compromise, hemodynamic instability was defined as hypotension or reduced tissue perfusion (capillary refill>2 sec) despite adequate fluid resuscitation and in need for significant inotropes /vasopressor support (>100mic /kg/min) of any inopressors. Criteria for AKI (based on AKIN criteria) were observed during the first 5 days of PICU admission |