الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Diabetic neuropathy and microangiopathy are common complications that can cause can cause central auditory processing dysfunction. Objective: to assess auditory cognitive function and central auditory functions in adults with type 2 diabetes mellitus (T2D). Subjects and methods: Sixty adult individuals with T2D participated as the diabetic group with sixty age and gender matched non-diabetic individuals as the control group. All subjects were submitted to full history taking, laboratory investigations (Fasting blood sugar, HbA1c and lipid profile), Mini-Mental State Examination (MMSE), basic audiological evaluation, behavioral central auditory processing (CAP) tests {Speech in Noise Test, the Dichotic Digits Test, Auditory Fusion Test and Auditory memory Tests}. In addition, cortical auditory evoked potentials (CAEPs) were conducted. Results: The diabetic group had high frequency SNHL, poorer discriminative ability, dichotic listening, temporal processing and auditory memory when compared to their non-diabetic peers. Lower MMSE scores as well as delayed latencies of CAEPs were found in the diabetic group compared to the control group. Patients with longer disease duration and patients with mild cognitive impairment (MCI) had poor behavioral CAP scores and delayed CAEPs latencies. No correlations were observed between MMSE, CAP scores, CAEPs latencies with HbA1C levels and lipid profile. Conclusions: Most of diabetic patients have MCI. Findings of the present study revealed the deteriorating effect of T2D on the CAP ability. Early detection of these complications is important to prevent more central and cognitive deterioration. More studies should be directed to avoid the DM complications on the CAP and cognitive levels |