الفهرس 
Clinico epidemiologic profile and treatment outcome of bladder cancer :retrospective analysis 2010-2016 (inclusive) at NEMROCK
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Abstract
Background: In Egypt, urinary bladder cancer incidence is among the highest worldwide, occupied the third rank for both genders and the second rank, after liver, among males. Objective: To assess clinico-epidemiological factors and to evaluate treatment modalities regarding the response, disease free survival, overall survival and toxicities in Egyptian patients suffering from urinary bladder carcinoma. Design: Retrospective study. Setting:KasrAl Ainy center of clinical oncology and nuclear medicine (NEMROCK).Patients and Methods: We collected data on patients who diagnosed with bladder cancer during the period from January 2010 till December 2016(included). Demographic, clinical and pathological variables and the type treatment modalities received were reviewed. Univariate and multivariate analyses were done with DFS and OS as the end points. Main outcome measure: Disease free survival and overall survival. Results: Of 303 patients for whom data was available, 204 patients were fit for radical treatment,155 patients (76%) underwent radical cystectomy, while 49 patients (24%) received radical radiotherapy. The median follow up was 10 months (range, 1-60 months) and median age was 61 years (range, 31-85). Of these patients, (87.1%) were males. In patients underwent radical surgery, the median DFS was 66 months, while the median DFS was17months in those who received radiotherapy as radical treatment but this was not statistically significant (p=0.686). On univariate and multivariate analysis, only the type of adjuvant therapy, especially adjuvant radiotherapy had an impact on DFS. It reduces the risk of recurrence by 80% (HR: 0.20 (95% CI 0.05- 0.8)