الفهرس | Only 14 pages are availabe for public view |
Abstract The purpose of this research was to determine how aqueous and ethanolic extracts of Nigella Sativa seeds and mulberry leaves affected metabolic syndrome. To fulfill the target of this study, a total of 36 rats were selected. They were split into six groups: group 1 is the control group, whereas group 2 is the induction group which have been fed on high fat diet supplemented with cholesterol powder and fructose in drinking water to induce metabolic syndrome, group 3:ethanolic Nigella Sativa extract treated group, group 4: aqueous Nigella Sativa extract treated group, Group 5:ethanolic mulberry leaves extract treated group, group 6: aqueous mulberry leaves extract treated group. Results obtained from this study showed significant improvement in metabolic disorders in groups of rats treated with either ethanolic or aqueous extracts of Nigella Sativa seeds and mulberry leaves as compared with induction group. The antioxidant activity of phenolic acids and flavonoids of both plants extracts in addition of anthocyanin content of mulberry extracts are responsible for this improvement. The results of histopathology revealed that there was damage in the heart, pancreas and liver in induction group. This damage was improved in treated groups with ethanolic and aqueous extracts. |