الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Improvement in survival has been linked to more aggressive treatment regimens. However, these protocols are associated with increased life-threatening complications that may require pediatric intensive Care units (PICU) admission. Nearly 40% of pediatric cancer patients require intensive care services, accounting for approximately 3% of all PICU admissions. Aim of the work was to evaluate predictors of outcome in PICU at pediatric oncology department, National cancer institute (NCI), Cairo university, and its relation to clinical characteristics of patients from 1st July 2013 to 30th of June 2014. Patients and methods: This retrospective study included 217 Pediatric cancer patient (166 male and 101 female) aged from one month to 24 years, who were hospitalized 267 episodes. Results: regarding type of tumor revealed no significant difference (P value >0.05) between died and improved patients. However, there was high significant difference between died and improved patients regarding PRISM (P-value 0.003), and PLEOD, number of organ dysfunction, inotropes and mechanical ventilation (P-value <0.001) and mortality was 34.8%. Conclusions: The high mortality rate between patients with multi-organ involvement leads to great benefits of early admission to PICU of children in whose signs of multi- organ involvement starts to develop |