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Abstract
Purpose: To evaluate the anatomical and functional benefits of internal limiting membrane (ILM) peeling during primary vitrectomy for patients with rhegmatogenous retinal detachment (RRD). Patients and methods: This is a prospective randomized comparative interventional study conducted on patients with RRD at Kasr Alainy hospital. Eyes with uncomplicated RRD undergoing primary vitrectomy were divided into 2 groups: group A: 20 eyes with ILM peeling, and group B: 23 eyes without ILM peeling.The primary outcome measures were the optical coherence tomography (OCT) morphological changes including: incidence of epimacular membranes (EMMs), vitreoretinal interface changes, intra-retinal/subretinal fluid (SRF), central subfield foveal thickness (CSFT) and the status of the ellipsoid zone. The secondary outcome measure was postoperative best corrected visual acuity (BCVA). Results: The Study was conducted during the time interval from Jan 2015 to Jan 2017. All patients achieved complete postoperative reattachment with mean BCVA was 1.0±0.4 logMAR (6/60) in group A, and 0.4±0.4 logMAR (6/15) in group B, which was statistically significant (p<0.001). Mean visual gain was 0.8±0.5 logMAR in group A, and 1.5±0.5 logMAR in group B, which was statistically significant (p<0.001). EMM did not develop in the ILM peeling group in any of the cases, while it developed in 17.4% in the non-ILM peeling group, which was statistically insignificant. Correlating RD duration to postoperative BCVA and to change in BCVA was statistically significant in group A