الفهرس | Only 14 pages are availabe for public view |
Abstract Osteoporosis is the most common metabolic bone disease worldwide and leads to physical, psychosocial and economic consequences. It can be seen in both genders and at any age, usually with older women (Harvey et al., 2010). Ear, which comprises of both the peripheral auditory and vestibular system, is housed in the temporal bone and consists of several bony segments. In cases with osteopenia and osteoporosis, changes in bone density, mass, and damping of the finely tuned motion mechanics of the middle ear can cause conductive hearing loss. Changes occurring in the optic capsule and the temporal bone due to demineralization might affect the inner ear and, therefore, cause sensorineural hearing loss (Sing et al., 2018). Due to a decrease in calcium concentration in the cupula and macula of the vestibular labyrinth, balance impairment could be a danger (Lee et al., 2017). So, this study was conducted to evaluate the auditory and vestibular function in patients with osteoporosis. Subjects in the current study were divided into: Reproductive group: which was subdivided in to - Control subgroup: Consisted of 34 normal females in the reproductive period aging [20-50] years old, not complaining of any audiovestibular symptoms. - Study subgroup: Consisted of 34 females in reproductive period in the age group of [20-50] years old, diagnosed as osteoporosis diagnosed by DEXA scan and classified into osteoporosis and osteopenia according WHO classification of osteoporosis . Females were included in this study even with or without audiovestibular symptoms Summary 75 Postmenopausal group: which was subdivided in to - Control subgroup: consisted of 34 normal females in the postmenopausal period aging [40-50] years old, not complaining of any audiovestibular symptoms - Study subgroup: consisted of 34 females in the postmenopausal period in the age group of [40-50] years old, diagnosed as osteoporosis by DEXA scan and classified into osteoporosis and osteopenia according WHO classification of osteoporosis. Osteoporotic females were included in this study even with or without audiovestibular symptoms. All subjects in the study group were subjected to the following: full history taking, otoscopic examination, QUALEFFO41, Office test examination, audiological evaluation (PTA, DPOAE). Vestibular evaluation (CVEMP, OVEMP, VHIT). Regarding the hearing function: PTA results: There was statistical significant difference between the control and the study subgroups in the frequency range (500-8000 Hz), with no significant difference between osteopenia and osteoporosis. In the postmenopausal group, there was statistical significant difference between the control and the study sub groups in the frequency range of 500-8000Hz with significant difference at (4 – 8 KHz) between osteopenia and osteoporosis. DPOAE results: most of the reproductive osteoporotic subgroup had preserved DPOAE and only one osteoporotic case of this group had absent high frequency DPOAE. In the postmenopausal study subgroup, one third of the cases had absent high frequency DPOAE with more affection in the osteoporotic than osteopenic postmenopausal females. Summary 76 Vestibular evaluation In the current study, O&CVEMP abnormalities were observed in 39 ears (57.35%) and 35 ears (51.47%) respectively in the reproductive study subgroup, While in the postmenopausal study subgroup, OVEMP and CVEMP abnormalities were observed in 43 ears (63.24%) and 38 ears (55.88 %) respectively. VHIT results: The current study reported few VHIT abnormalities. The reproductive study subgroup low gain abnormalities were reported in the lateral canal in one ear and also the posterior canal in one ear. While the postmenopausal study subgroup low gain abnormalities were reported in the lateral canal of 2 ears, the posterior canal in 3 ears and the anterior canal only in one ear. With no correction saccades were reported in all reproductive and postmenopausal study subgroups. from the results of our study, we can conclude that osteoporosis affect the audiovestibular system wither there is a complaint or not. |