الفهرس | Only 14 pages are availabe for public view |
Abstract Pseudofolliculitis barbae (PFB) is a chronic inflammatory disorder occurring mostly in regions of thick hair growth after shaving. PFB is characterized clinically by multiple painful, pruritic erythematous papules and, less commonly, pustules, nodules, or abscesses. Aim: To evaluate the efficacy of topical Eflornithine cream only, long-pulsed Nd-YAG laser, versus their combination for PFB management. Patients and Methods: Overall, male patients with PFB were allocated into three treatment groups; group (n= ): Treated by topical Eflornithine cream twice daily for weeks, group II (n= ): Treated by Long-pulsed Nd-YAG laser for sessions weeks’ interval, group III (n= ): Treated by their combination for weeks. These patients were evaluated after weeks and for a further weeks through serial photographs, Folliscopic evaluation, and a quartile grading system for improvement. Results: After weeks of treatments, the mean improvement percentages of the inflammatory papules, as well as hair density in the Long-pulsed Nd-YAG laser + Eflornithine cream, treated group was significantly higher compared with either Eflornithine cream treated group or laser only treated group. The same relationship was demonstrated after weeks of follow-up but with lower improvements compared with weeks of treatment outcome. Conclusions: Topical Eflornithine cream exerts an additive effect on long-pulsed Nd-YAG laser in enhancing the rate and degree of hair reduction and inflammatory papules in PFB cases with a further follow-up improvement. This combined approach should be long-established in larger sample sizes and long-term studies. |