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Abstract The aim of the present study to evaluate the correlation of fundus autofluorescence in diabetic macular edema with its functional changes. cases with untreated clinically significant macular edema underwent best corrected visual acuity determination ,slit lamp biomicroscopy, fluorescein angiography, optical coherence tomography (OCT; mean central retinal thickness, volume, and DME pattern), fundus autofluorescence (FAF; absent or increased iFAF, single or multiple spots, iFAF area quantification) and (10-2) humphery visual field analyser . This study highlights the correlation between fundus autofluorescence with visual field changes and FAF with optical coherence tomography |