الفهرس | Only 14 pages are availabe for public view |
Abstract Gestational diabetes mellitus (GDM) is carbohydrate intolerance resulting in hyperglycemia with onset or first recognition during pregnancy excluding overt diabetes in early pregnancy. GDM complicates approximately 6% of pregnancies and is associated with adverse health outcomes for the mother, fetus, and newborn. Fetal complications of GDM include macrosomia, shoulder dystocia, intrauterine fetal death, neonatal hypoglycemia, congenital anomalies, and respiratory distress syndrome. Maternal complications of GDM as birth trauma, increased rate of cesarean section, also women with GDM have a higher rate of postpartum diabetes. In addition, it can lead to long-term consequences such as the development of type 2 diabetes, cardiovascular risk, and metabolic syndrome. So, screening for GDM and its early detection and treatment can prevent and reduce harm to both the mother and the baby. The American College of Obstetricians and Gynecologists (ACOG) continues to recommend a two-step screening and diagnostic process for gestational diabetes mellitus (GDM), with a 50-g glucose challenge test (GCT) for screening during weeks 24–28 of gestation, followed by a diagnostic 100 g, 3-hour glucose tolerance test (GTT) for those with GCT results ≥ 140 mg/dL. This study was a prospective cohort study to investigate the impact of positive glucose challenge test on perinatal morbidity. A total of 200 Pregnant women (gestational age 24 – 28 weeks) with high risk for diabetes attending antenatal care in the outpatient clinic at Ain shams university maternity hospital involved in this study. 200 pregnant women screened for gestational diabetes (GDM) using 50-gram GCT, at 24–28 weeks gestation, followed by 100 gm 3h OGTT only if GCT was positive. |