الفهرس | Only 14 pages are availabe for public view |
Abstract This study was performed to evaluate the expression of claudin 4 in oral squamous cells carcinoma (OSCC), as well as to identify the correlation between expression of this marker and the histological grade of OSCC. Thirty archival cases of OSCC and 10 cases of epithelial hyperplasia (control group) were investigated in the present study. The OSCC cases were classified into well (10 cases), moderately (10 cases) and poorly (10 cases) differentiated OSCC. Histological examination using hematoxylin and eosin stain was performed. For immunohistochemical examination, streptavidin- biotin method was used and the cases were stained with anti claudin-4 monoclonal antibody (Cat#RB-9266-P0). The Mouse Immunocruz Staining System immunodetection kit (SC-2050) was also used. |