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Abstract
Coronary artery bypass grafting using cardio pulmonary bypass is a successful procedure in modern medicine, however prolonged aortic cross clamp time is linked to adverse outcome following cardiac surgery. During aortic cross clamping, a period of global myocardial ischemia is followed by reperfusion injury that manifests as myocardial stunning, arrhythmia and changes in cardiac performance that needs inotropic support in early post - operative period, also associated with acute lung injury that needs mechanical ventilation of different duration. To assess the effect of the aortic cross clamp time on the mechanical ventilation and inotropic support post-operatively. Thirty elective patients of isolated ischemic heart disease undergoing on pump CABG collected from cardio thoracic surgery department Elkasr Alainy Hospital. We assessed the post - operative ventilation time and inotropic support of those patients post - operatively. Statistical analysis showed, when the mean time of the cross clamp was(± 73minutes) there was no usage of postoperative inotropes and the mechanical ventilation time was only up to one day in twenty five patients (83.33%), but with increased the time of the cross clamp, when the mean time was (± 135 minutes) the usage of post-operative inotropes was mandatory in three patients (10%) and the post-operative ventilation was up to three days in four patients about 16%