الفهرس 
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Abstract
The current study aimed to study circulating CoQ10 level in coronary artery disease patients undergoing coronary angiography and assess its relation to disease severity. The relation of Galectin-3 and MDA is also studied. The present study is conducted on two groups of subjects based on cardiac catheterization: 1. Patients group: 50 subjects with positive coronary angiography finding; obstructive coronary artery disease (OCAD). This group comprised of 38 male (76.0%) and 12 female (24.0%) and their mean age is 59.10 ± 10.81. 2. Control group: 39 subjects with normal coronary angiography (NCA). This group comprised of 23 male (59.0%) and 16 female (41.0%) and their mean age is 55.69 ± 8.79. Both groups were subjected to clinical examination, routine laboratory investigation, creatinine, fasting blood glucose, lipid profile, MDA & serum assay of CoQ10 and Galectin-3 by ELISA kit. Our results revealed: CAD cases had significantly higher frequency of hypertension and median BMI value. CAD cases had significantly higher frequency of unstable angina, old MI and median EF. Statistically significantly higher levels of TLC, TC, TG, LDL-cholesterol, TC/HDL and LDL/HDL in CAD group compared to NCA group. On the other hand, hemoglobin and HDL-cholesterol are significantly decreased in CAD group compared to NCA group. CoQ10 is significantly reduced in CAD group compared to NCA group. On the other hand, both Galectin-3 and MDA are significantly elevated in CAD group compared to NCA group. CoQ10 is significantly reduced in high syntax group compared to low and intermediate groups. On the other hand, both MDA and galectin-3 are significantly elevated in high syntax group compared to low and intermediate groups. Gensini score is significantly elevated in high syntax group compared to low syntax group.