الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Vitamin D is a fat soluable vitamin which is important for different systems of the human body including endocrine and immune systems, vasculature, endothelial function and wound healing. Aim of the work: is to asses the relationship between vitamin D deficiency and incidence of hypertrophic scar and to determine the effect of vitamin D replacement therapy on hypertrophic scar width and scale in patients who have deficiency in vitamin D. Methods: 30 Patients with vitamin D deficiency < 25ng/ml with hypertrophic scars were divided into 2 groups each group included 15 patients. First group were subjected to oral vitamin D replacement (2000 IU) daily for one month and the second group received placebo (sugary tablets). Results: Data from 30 subjects suggested that scar improvement occurred significantly with p value < 0.05 after vitamin D replacement in group (1) and this was represented by low level of Vancouver score but scar width did not change after treatment in both study groups. Conclusion: Vitamin D supplement can be used as an adjuvent treatment for hypertrophic scars as it reduce vascularity, pliability, pigmentation, and height of scars with little effect on scar width. Key words: Vitamin D – hypertrophic scarring. |