الفهرس | Only 14 pages are availabe for public view |
Abstract Contrast induced nephropathy (CIN) occurs due to acute kidney injury caused by the contrast media and is a common cause of hospital-acquired acute renal failure.CIN is defined as a 25% increase in serum creatinine from the baseline value, or an absolute increase of at least 0.5 mg/dL (44.2 mmol/L), 48 - 72 hours after the administration of radiographic contrast media that is not attributable to other causes. Application of risk scoring systems can prognosticate the high risk patients for CIN after the exposure to contrast. Though there are various risk scoring systems available for prediction of CIN, the risk factor profile and their cumulative effect inacute coronary syndrome patients. In this study , three scores were done to early predict contrast induced nephropathyCHA2DS2 VASc , Mehran and GRACE scores were compared in total 648 patients with acute coronary syndrome.CHA2DS2=VASc showed the highest specificity prediction (100%) among the three studied scores, while GRACE score showed the highest sensitivity prediction (60%).The highest goodness of fit is for the combination of CHA2DS2-VASc and GRACE Score for CIN prediction (R2= 0.899, followed by prediction by CHA2DS2=VASc alone (R2= 893). so both scores can be used as independent predictors for CIN. |