الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Diabetic ME is the commonest cause of lost vision resulting fromDR. It poses a real challenge in its diagnosis and management owing to the high financial impact it has on health care systems worldwide.
The present study was conducted on a total of 100 eyes of 50 subjects having DME with aiming to compare between the three different imaging modalities FFA, OCT and OCTA in diagnosis of Diabetic Macular Edema regarding the appearance of macular edema, Foveal Avascular Zone and retinal ischemia in FFA, SCP and DCP.
All cases in our study underwent standard ophthalmologic assessment emphasizing on BCVA, anterior segment assessment by slit lamp biomicroscope, fundus examination following full pupillary dilation and retinal imaging with FA using (Spectralis; Heidelberg Engineering, Heidelberg, Germany) and OCT/OCTA imaging using (Cirrus HD-OCT; Carl Zeiss Meditec, Dublin, CA, USA).
The age of the patients was from 40 y - 77 y at the time of examination. (mean, 60.99 years± 8.60).
All subjects had moderate to severe Diabetic macular edema with Central foveal thickness ranged from 142.0 – 856.0 (mean, 358.29 ± 136.365) microns as measured by SD-OCT. 61 eyes (61%) had center involving DME, while 39 eyes (39%) had non-center involving DME.
Detection of ischemia was based on ETDRS grid in foveal and para foveal areas. The DCp was the first layer to shows signs of ischemia, followed by the SCP and lastly the FFA.
OCTA shows sometimes low reliability and poor visualization of the DCP in cases suffering ME. However, the OCTA information might help investigating the pathogenesis of DME if carefully interpreted.
The ischemia detected in the DCP correlates with the BCVA of the patients, which explains the decline in vision in early DME.