الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Paralysis of the facial nerve causes functional and emotional problems to the patients, treatment methods need to be improved. Aim of the study: The aim of this study was evaluate the effects of PRF on peripheral nerve regeneration in the facial nerve of rats by using functional and histopathologic analyses. Materials and Methods: seventy-two Sprague Dawely rats with average weight of (250---300 g), were divided randomly into four groups: group 1(control) the specimen from facial nerve trunk was taken to be a reference, group 2 (cutting) the facial nerve was transected and left without any treatment, group 3 (suture) the facial nerve was transected then the two ends of the nerve was sutured with (8-0) suture, group 4 (PRF) the facial nerve was transected then the two ends of the nerve was sutured with (8-0) suture then a PRF membrane was wrapped over the sutured area. Results: PRF group showed better bundles organization with no fatty adhesion with surrounding inflamed area compared with cutting group at 4th week. |