الفهرس | Only 14 pages are availabe for public view |
Abstract Several methods were proposed to identify parathyroid glands in order to decrease the incidence of postoperative hypocalcaemia. Methylene blue is certified by the US Food and Drug Administration. It can be used in a variety of medical treatments. Parathyroid glands can absorb the stain then regain their original yellow colour in three minutes. In comparison, thyroid tissues took 15 minutes to return to normal, and fat and muscles took over 25 minutes. The authors suggested that parathyroid glands can absorb methylene blue faster than other tissues because they have a dense lymphovascular pattern. Thus, the current study aimed to evaluate the safety and reliability of the methylene blue spray technique in the identification of parathyroid glands during thyroid operations. This was a prospective study conducted on 110 patients diagnosed with simple or toxic nodular goitre requiring surgery who were undergone total thyroidectomy in the Surgical department Menoufia University Hospital. This study revealed the following results: • The mean age was 48.17±6.41. • Most of the studied cases were female (72.7%) while only 27% of which were males. • MNG was the most common pathology (54.5%) followed by PTC (25.5%) and lastly solitary thyroid nodule which represented 20%. All the studied cases were undergone operation for total thyroidectomy. • The mean value of one day post-operative serum calcium, Post operation 4 hours parathyroid hormone were 8.84±0.98 and 68.84±20.39 respectively. • Most of cases the studied cases were positive following 5 minutes after methylene blue spray (93.6) which indicated that could be used as reliable tool for parathyroid gland identification. • No recorded adverse events or allergic manifestations were recorded to the methylene blue spray. • Only 5% of the studied cases developed hypocalcaemia. • Methylene blue has could detect parathyroid gland with moderate sensitivity and higher specificity and accuracy |