الفهرس 
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Abstract
With several waves of infections in many different countries, COVID-19, which originally emerged in Wuhan, China in November 2019, had a protracted course. Healthcare facilities witnessed an unprecedented patient load due to COVID-19. SARS-CoV-2 basically targets the respiratory system, which can result in mild to severe pneumonia. Conventional oxygen therapy can be utilized initially for people with hypoxemia. High flow nasal cannulas can be used for patients who show greater labor of breathing or who remain hypoxic after these therapies.
HFNC therapy is one of the most frequently employed ventilation methods in COVID-19 pneumonia and respiratory failure, however, delaying the intubation timing could be harmful and may cause clinical deterioration, likely due to self-inflicted lung injury caused by continued non-invasive ventilation with atelectasis.
Given that delays in intubation and mechanical ventilation might result in increased mortality rates, it is essential to employ relevant methods to predict the success or failure of this kind of respiratory support.