الفهرس | Only 14 pages are availabe for public view |
Abstract Parkinson’s disease (PD) is an important neurodegenerative disorder, due to its progressive neurodegeneration of dopaminergic neurons in the substantia nigra of midbrain. Rotenone is a natural compound used as an insecticide induces neurochemical, neuropathological and behavioral features of PD in rats. This is due to alpha-synuclein aggregation in the dopaminergic neurons leading to depletion of the neurotransmitter; dopamine with cell degeneration. Ginkgo biloba is a widely used herbal medicine. It possesses neuroprotection, anti-oxidant, and membrane stabilization effects. |