Author: Salib, Youstina Samuel./ Title: Comparative Histological and Immunohistochemical Study on the Effect of Ginkgo Biloba Extract versus Mesenchymal Stem Cells on the Substantia Nigra of Brain Stem of Experimentally Induced Parkinson’s Disease Model in Adult Male Albino Rat /

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العنوان

Comparative Histological and Immunohistochemical Study on the Effect of Ginkgo Biloba Extract versus Mesenchymal Stem Cells on the Substantia Nigra of Brain Stem of Experimentally Induced Parkinson’s Disease Model in Adult Male Albino Rat /

المؤلف

Salib, Youstina Samuel.

هيئة الاعداد

باحث / يوستينا صموئيل صليب

مشرف / عبد المنعم فريد زمزم

مشرف / ابتسام فؤاد عبد المجيد عكاشة

مشرف / سماح قنديل السيد قنديل

مشرف / هبة السيد محمد شرف الدين

الموضوع

Histology

تاريخ النشر

2023.

عدد الصفحات

339 p. :

اللغة

الإنجليزية

الدرجة

الدكتوراه

التخصص

علم الأنسجة

تاريخ الإجازة

25/2/2024

مكان الإجازة

جامعة طنطا - كلية الطب - هستولوجيا

الفهرس

Only 14 pages are availabe for public view

from

389

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389

Abstract

Parkinson’s disease (PD) is an important neurodegenerative disorder, due to its progressive neurodegeneration of dopaminergic neurons in the substantia nigra of midbrain. Rotenone is a natural compound used as an insecticide induces neurochemical, neuropathological and behavioral features of PD in rats. This is due to alpha-synuclein aggregation in the dopaminergic neurons leading to depletion of the neurotransmitter; dopamine with cell degeneration. Ginkgo biloba is a widely used herbal medicine. It possesses neuroprotection, anti-oxidant, and membrane stabilization effects.