الفهرس | Only 14 pages are availabe for public view |
Abstract The anatomical SYNTAX (Synergy between percutaneous coronary intervention with taxus and cardiac surgery) score is an angiographic scoring system for assessing the complexity of coronary artery disease (CAD) while SYNTAX II score included both anatomical and clinical variables D-dimer is the end product of plasmin-mediated degradation of cross-linked fibrin. Plasma concentrations of D-dimer, a marker of coagulation, are dependent on fibrin generation and subsequent degradation by the endogenous fibrinolytic system. Several studies have suggested that elevated D-dimer levels are associated with adverse outcomes in patients hospitalized for myocardial infarction. The current study was conducted to detect the relation between the serum Level of D-dimer upon admission and the severity of coronary artery disease in patients with ST segment elevation myocardial infarction. The current study included 120 patients with ST segment elevation myocardial infarction who were recruited from Cardiology Department, Menoufia University Hospital and Banha Teaching Hospital. in the current study, the mean SYNTAX II score was 27.82 ± 5.20 and there were 57 cases (47.5%) with low SYNTAX II score (SYNTAX II score < 25) and 63 cases (52.5%) with High SYNTAX II score (SYNTAX II score ≥ 25). The D-dimer level was statistically significantly higher in the cases with high SYNTAX II score as compared to the cases with low SYNTAX II score (p< 0.001). The best cutoff point of D-dimer level to identify cases with high SYNTAX II score was > 1.75 mg/L with 73.5% sensitivity and 64.5% specificity. The area under the curve was 0.701 and this value showed a statistically significant value (p = 0.001). |