الفهرس | Only 14 pages are availabe for public view |
Abstract Acute ischemic stroke is an uncommon but often major complication of percutaneous coronary intervention (PCI) with a major impact on mortality and morbidity post-PCI. Independent predictors of stroke following PCI include age, female sex, and prior history of stroke or transient ischemic attack (TIA) The relative risk of stroke is elevated during the first 2 days and then declined gradually at 4 to 8 weeks after PCI. The primary ischemic mechanism of PCI stroke is embolization rather than hemodynamic instability. proximal embolism mostly affecting the MCA territory caused the majority of radiologically confirmed ischemic strokes after PCI According to current guidelines, the Administration of IV tissue plasminogen activator(tPA) is the recommended standard of care in acute ischemic stroke during the first 4.5 hours from stroke onset. However, they exclude intravenous IVT in heparinized patients with an activated partial thromboplastin time (aPTT) greater than 40 seconds As a result, there are no current guidelines for the management of patients who develop stroke after PCI. |