الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Pediatric rhegmatogenous retinal detachments (PRRDs) are complex, rare occurrences and are often related to trauma or congenital abnormalities. Children often do not recognize or report symptoms of retinal detachment. Thus at presentation, PRRD is typically advanced often with macular involvement, proliferative vitreoretinopathy (PVR), chronic duration, and poor visual acuity. Because 5-FU and LMWH are effective in different aspects in the PVR process, it was believed that a syngergistic approach to the prevention of PVR would be advantageous.
Although the efficacy of both chemicals was tested in multiple previous studies with varying results, as far as the authors are aware of, they were not tested in pediatric retinal detachment which is usually associated with high incidence of PVR, also in vivo assessment of photoreceptor toxicity through ERG was not correlated with clinical outcomes.