الفهرس | Only 14 pages are availabe for public view |
Abstract Acrylamide first received global attention in April 2002 when Swedish researchers reported finding the chemical in fried and ovenbaked foods, especially in potato chips and French fries. The findings were at first greeted with skepticism, but scientists in other nations have since produced similar results. In the present study, One hundred & seventy fertile male and virgin female mice weighing approximately 25g. body weight were used. They were mated with average of 3: 1 females per each male respectively and zero date of gestation was determined. Pregnants were arranged into 6 groups as follows: 1. Control pregnants at 14, 16 & I 7-days prenatal as well as at parturition. 2. 25 μgm acrylamide/ kg.-treated group : each daily administered from 6th day of gestation till 14, 16 & : 7 days prenatal as well as at parturition. 3. Experimental group fed on diet containing 50% fried potato chips from 6th day of gestation till 14, 16 & 17 days prenatal as weil as at parturition. 4. Experimental group fed on diet containing 15 % Nigella sativa seed from 6th day of gestation till 14, 16 & 17 days prenatal as well as at parturition. 5. Experimental group fed on diet containing 15 %Nigella sativa seed and received acrylamide-treatment from 6th day of gestation till 14, l 6 & 17 days prenatal as well as at parturition. 6. Experimental group fed on diet containing 15 % Nigella sativa seed and fried potato chips from 6th day of gestation till 14, 16 & 17 days prenatal as well as at parturition. At the mentioned periods of gestation, prenatal fetuses 14, 16 & 17- days fetuses and delivered newly born were separated of both control and experimental groups as well as selected maternal and newly born organs at parturition and subjected for histological investigations . |