الفهرس | Only 14 pages are availabe for public view |
Abstract Glomerulonephritis is a disease of increasing importance as it is one of the commonest causes of end stage renal failure. The response to therapy, course of the disease and its outcome depend largely on the etiologic causes and histopathologic types. In several reported series of patients with RPGN, the authors have attempted to determine prognostic factors and the effect of treatment. These series are not strictly comparable, because there are variation in:- ^ 1) The criteria of the diagnosis. 2) The underlying immunopathogenetic processes. 3) The extent of crescent formation (>30% crescents, > 50% crescents, or > 80% crescents). 4) The inclusion or exclusion of clinically suspected microscopic vasculitis or Goodpasture’s syndrome. Moreover, a valid life table analysis of persistance of renal function and survival of patients have rarely been undertaken. The rarity of studies about the factors which affect the kidney function and the patients survival and the depate arround the risk factors in cases of crescentic glomerulonephritis encouraged us to study our cases of crescentic glomerulonephritis followed up for long period (between 1986-1996) to deterine the risk factors on the kidney function and the patients survival. We in a retrospective studied the clinical and histopathological variables of all patients at presentation and correlate them with the kidney function and the patient survival at termination of the study. In conclusion univariate revealed that the risk factors which affected the kidney function in our cases of crescentic GN were:- - The serum creatinine at presentation. - The percentage of the glomeruli affected by crescents. |