الفهرس 
INTRODUCTION AND AIM OF THE WORKOnly 14 pages are availabe for public view
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Abstract
Malignant transformation is accompanied by phenotypic changes in the invloved cells including the loss of normal cell surafce antigenic component and gain of neoantigens. These neoantigens are capable of evoking an immune response. The immune response may be humoral or cell-mediated. In malignancy, the cell-mediated immune response is of particular importance for initiating the reaction of the body to a tumour and is brought about by the T-Iymphocytes. In cancer patients the cell-mediated immunity may be altered by the presenc~ of the tumour. So, the present work was carried out to evalute the immunocmpetence of patients with solid tumours before the start of any kind of therapy. to determine if there is any difference in the parameters of cell-mediated immunity between cancer patients and normal healthy control. Also, to know the relation between the stage of the disease and the pre-treatment immunolog.ic state. The study was performed on 50 patients with solid tumours (twenty five cases with breast cancer, sixteen cases with colorectal cancer and nine cases with malignant lymphomas), in addition to 50 normal and healthy persons (controls) .