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العنوان
Biochemical and immunological studies on patients eith pulmonary tuberculosis /
المؤلف
Mohafez, Omar Mahmoud Mohamed.
هيئة الاعداد
باحث / عمر محمود محمد
مشرف / حسنى على حسنى
مناقش / احمد حامد محمد
مناقش / عمر الاحمدى محمد العسوى
الموضوع
Biochemistry. Pulmonary tuberculosis.
تاريخ النشر
1999.
عدد الصفحات
91 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات (المتنوعة)
الناشر
تاريخ الإجازة
28/11/1999
مكان الإجازة
جامعة أسيوط - كلية الصيدلة - biochemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

The levels of IL-10 were found to be increased significantly in TB serum when compared with controls (p<0.001), Also, the levels oSIL-10 were found to be increased significantly in pleural effusion when compared with serum the same patients (p<0.01).
The levels of ADA were found increased significantly in serum from IB patient than those of controls. (p<0,001). Also higher level of ADA was found in pleural effusion than in serum from (he same patients (p<0.05).
A significant higher level of NO was found in TB serum than control (p<0.001). However; a significant lower level was found in pleural effusion when compared with serum from the same patients (p<0.00l).
In conclusion patients with pulmonary TB have marked disturbances in cytokines in the form of INF-y, TNF-a and IL-10 together with enhanced levels of the inflammatory mediators NO. Meanwhile, the activity levels of : ADA are also increased. These items would reflect immune reactions in these patients.