Search In this Thesis
   Search In this Thesis  
العنوان
A study on the role of some binders on granule characteristics in tablet formulations /
المؤلف
Abd El-Alim, Hamdy Mohamed.
هيئة الاعداد
باحث / حمدى محمد عبدالعليم
مشرف / عبدالحليم جسين غنيم
مشرف / حسن محمد الصباغ
مناقش / عبدالحليم جسين غنيم
مناقش / حسن محمد الصباغ
الموضوع
pharmaceutics. Tablet.
تاريخ النشر
1982.
عدد الصفحات
158 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الصيدلة ، علم السموم والصيدلانيات (المتنوعة)
تاريخ الإجازة
1/1/1982
مكان الإجازة
جامعة المنصورة - كلية الصيدلة - علم الصيدلانيات
الفهرس
Only 14 pages are availabe for public view

from 198

from 198

Abstract

Wet granulation may be required to produce uniform colored tablets and tablets containing potent drugs in low dosage level with minimal intertablet variation. As most studies involving binders are concerned mainly with the properties of the tablets such as weight uniformity, mechanical strength and disintegration time a scant work was made for comparing the mechanical properties of the granules, the crushing force of the tablet and the compres­sion behaviour. Thus, the object of this investigation was to study the influence of binders on the physical characters and tablet properties of certain commonly used diluents and drugs such as sulfadiazine and phenazopyridine hydrochloride. To fulfill this goal, the work in the thesis embraces the following : Part I : Effect of binders on granules and tabletsproperties of certain diluents.