الفهرس | Only 14 pages are availabe for public view |
Abstract The work described in this thesis has been undertaken with the aim of searching of naturally occurring substances from some available plants in Egypt as a source of drugs. Extracts of two selected plant specie were studied, these are Cynanchum acutum L. (Asclepiadaceae) and Curcuma longa L. (Zingiberaceae). Through this investigation, useful information was obtained from the application of various chromatographic methods, such as CC and PTLC, as well as spectroscopic methods, such as MS, GC/MS, 1H NMR, UV and IR. Processing of Cynanchum acutum L. revealed the isolation and structure elucidation of fifteen compounds including two coumarins. This is the first report indicating the presence of coumarins from the genus Cynanchum. Processing of Curcuma longa L. revealed the isolation and structure elucidation of seven compounds including gingerdione. This is the first report indicating the isolation of gingerols (compound 19) from Curcuma longa. The petroleum ether and chloroform extracts of Curcuma longa are studied for insecticidal and antifeedant activities against the confused flour beetles, Tribolium confusum, where the petroleum ether extract was proved to be active while the chloroform fraction was inactive. The bioassay results showed that both 1-dehydrogingerdione 19 and curcuma oily fraction which were isolated from the pet. ether fraction of Curcuma longa were highly effective insecticidal against the confused flour beetles, Tribolium confusum |