الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Orthotropic liver transplantation is the replacement of a diseased liver with a healthy liver and currently represents the treatment of choice in patients with end-stage liver disease either acute or chronic including HCC for which no other therapy is available. Liver transplantation either from cadaveric or living donors has advantages and disadvantages including moral, ethical, social and religious objection in each type. However, LT has many contraindications to liver transplantation either absolute or relative ones. Absolute CI include uncontrolled sepsis, Lack of compliance, Malignancy, severe irreversible comorbidity, Active alcohol and drug intake, Anatomic anomalies precluding LT and severe AFHF. Living donor selection and evaluation is the most important processes in living donor liver transplantation, is carried out to assure the donor safety; adequate residual liver volume; hence decreasing morbidity and mortality of donors; and the high-quality, suitable; and sufficient liver grafts for recipients. No exceptions to this rule, regardless of the consequences for the recipient, even death. This should be done by separately designated donor team including surgeon, hepatologist, psychiatric and social worker. Evaluation is consisting of multiple stages ranging from three to six and including clinical, labarotory, radiological, endoscopic, histological, social, mental, psychological and anesthetic fitness assessment. The causes for donor exclusion divided to donor-related factors and recipient- related factors. Reasons for donor rejection can be divided into non-pathological, pathological and psychosocial causes. However, the range of marginal living-liver donors may be safely used to expand donor pool when there are no other alternatives. LLDs complications defined as postoperative event is considered as a complication only if it required an invasive interventional procedure, a change in medications from the routine postoperative protocol or prolonged hospital stay beyond 10 days. Most complications occurring after liver donation in the early postoperative period and do not usually require interventional or surgical treatment. Although complications from liver donation are not uncommon, most are minor and, with medical or interventional management have no long term sequelae or long-term hepatic dysfunction; so LDLT is a relatively safe procedure. Prevention of these complications is the best way to improve postoperative outcome by preoperative assessment of anatomy and anomalies, donor evaluation, vascular occlusion, cell saver, meticulous surgical manover, LMWH, postoperative physiotherapy, measures to help residual liver regeneration OLT is unavoidable solution for treatment of variable liver diseases when no available substitutions. DDLT is unable to supply sufficient organs for these patients, so, LDLT is the best way to expand organ pole to yield this deficiency of organ shortage, and however LLD morbidity and mortality is unavoidable. Adequate selection and evaluation, excellent perioperative management is obligatory to minimize this morbidity and mortality and yield satisfactory quality of life.