الفهرس | Only 14 pages are availabe for public view |
Abstract By conducting this research in the same manner as the glucose tolerance test it has been possible to distinguish the presence of three types of ascorbic acid tolerance curves for normal individuals. Each curve reflects the vitamin C status of the body i.e. the degree of vitamin C saturation.The rate of utilization of the vitamin in the three cases of vitamin C tolerance curves has been observed and it has been concluded that there is an increased rate of utilization of ascorbic acid in the undersaturated individuals with Virtually little or no ascorbic acid excretion i.e a low rate of urinary excretion. While in the moderately saturated individual there is a lower rate of uptake by the tissues and a higher rate of urinary excretion.In the saturated individuals exhibiting Type (3) tolerance curves, there is no detectable rate of utilization from the curves (no decline ,With persisting rise),since the tissues are saturated and will not accept ascorbic acid presented to it.On the other hand there is a very high rate of urinary excretion since the rate of intestinal absorption of the vitamin is equal or less than the rate of the vitamins excretion. (us) CONCLUSION , If the tissue ascorbic acid content is low then upon administration of Vitamin C there will be a rapid flow of the vitamin from the plasma to the tissues i,e a high rate of utilization and virtually little or no excretion of the vitamin in the urine i.E a decreased rate of urinary excretion.On the other hand if the individual is relatively saturated then the rate of tissue uptake of the vitamin will exhibit itself only after absorption is complete,followed by a high rate of urinary excretion with a fall in the rate of both uptake and excretion at the end of the experimental period. In saturated persons there is avery high rate of urinary excretion with no rate of utilization as the tissues are saturated and will not take up any vitamin C presented to it,i.e no rate of utilization. |