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Abstract Meniere’s disease was described by Prosper Meniere in 1861. It was defined as a membranous labyrinth disease, characterized by recurrent spontaneous episodes of vertigo, hearing loss, ear fullness and tinnitus on the affected side owing to endolymphatic hydrops. Endolymphatic hydrops is most frequently found in the cochlea and saccule is the second most prevalent site of affection. Severe hydrops is more common in the saccule. Saccular hydrops may occur in 50% of the cases of Meniere’s disease. The definition of saccular hydrops may represent an important breakthrough in the diagnosis of Meniere’s disease. After one hundred and fifty years of the first describtion of the disease, many aspects concerning etiopathogenesis and therapy of Meniere’s disease are still controversial. |